Protein analytics

In order to guarantee patient safety for new drugs and medical products, refined analysis methods are necessary. Our interdisciplinary experts accompany and evaluate your new developments with highly developed analytical methods.

 

Patient safety through medical devices tested at OFI

In addition to client-funded research & analysis, we offer protein analysis under GMP with state-of-the-art methods and equipment:

  • Protein identification
  • Protein quantification
  • Peptide Mapping
  • Immunological methods (ELISA)

 

Our services in protein analysis

Pharmaceuticals

  • Release analysis of biopharmaceutical and biosimilar batches after authorisation
  • Complete determination of the protein sequence - Peptide Mapping
  • Qualitative and quantitative analysis of APIs and identification of by-products and impurities
  • Quantitative determination of deamidation
  • Analysis of protein expression profiles from biological and in-vitro matrices
  • Characterization of the accumulation of therapeutic proteins

 

Allergens

  • Determination of denaturing potential
  • Adsorption behaviour on materials
  • Benchmarking and comparative measurement of proteins and materials

 

Medical devices

  • Inflammatory and sensitization potential of materials
  • Influence on the expression of inflammatory factors, e.g. IL 1ß, IL 8 in cell cultures and skin models